George Popham Sewall (1811–1881) was an American lawyer and State Representative from Old Town, Maine. He was born in Georgetown, Maine the son of Joseph and Hannah Shaw Sewall.
He was elected Speaker of the Maine House of Representatives in 1851 - 1852. He was appointed U.S. Collector of Customs for Bangor, Maine in 1854. His great grandson, Joseph Sewall, later became President of the Maine Senate. His wife, Sydney Ellen Wingate, was the daughter of U.S. Representative Joseph F. Wingate. Their son James Wingate Sewall started the forest engineering practice that became James W. Sewall Co. George Sewall died in Old Town in 1881.